The blast occurred in a roadside storehouse in the Ezhangtan area of Baiyun district of Guangzhou City. The cause of the blast is not known yet.
Rescuers have found the remains of four bodies at the scene while fourteen others were taken to hospital, state-run Xinhua news agency reported.
Windows of a nearby shopping mall were smashed due to the explosion. Heavy smoke could still be seen coming from the site two hours after the explosion, with fire fighters struggling to put out the blaze.
This is the second explosion that has rocked China in as many days.
A huge explosion yesterday in front of a primary school in south China's Guangxi Zhuang Autonomous Region killed at least 2 persons and injured 44 others, including 26 students.
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