However, other Indians in the fray -- B Sai Praneeth, H S Prannoy and P C Thulasi -- advanced to the second round of the tournament after registering contrasting victories on the opening day of the main draw.
World No. 8 Saina fought for an hour and two minutes before losing 21-16 15-21 11-21 to her lower ranked Japanese rival.
Saina, seeded seventh, started the second game also well as she took a 4-2 lead. But the Japanese quickly got her act together and from tied 4-4 position, she surged ahead to 10-4.
Thereafter, the Indian was always on the backfoot and was playing the catching-up game. Hirose finally stole the game 21-15 to take the match to the decider.
In other women's singles first round matches, Arundhati Pantawane fought hard before going down to another Japanese Shizuka Uchida 21-16 11-21 15-21 in just over an hour, while top seed and Olympic champion Li Xuerui of China made mincemeat of Tanvi Lad during her 21-6 21-11 win.
However, P C Thulasi notched up a 21-13 21-16 victory over New Zealand's Anna Rankin to set up a second round clash with world number two Chinese Yihan Wang, who was the runners-up at the India Super Series last week.
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