The 30-share index was trading down by 103.90 points, or 0.37 per cent, to 27,782.31 with stocks of healthcare, IT, teck, FMCG, auto and banking sectors leading the fall. The gauge had lost 1,158.23 points in the previous four sessions.
On similar lines, the National Stock Exchange Nifty shed 42.30 points, or 0.50 per cent, to 8,405.80.
Brokers said persistent selling by participants following weak earnings by some companies mainly dampened the sentiment.
Among other Asian markets, Hong Kong's Hang Seng rose by 1.14 per cent and Japan's Nikkei moved up by 0.90 per cent in early trade today.
The US Dow Jones Industrial Average ended 1.17 per cent higher in yesterday's trade.
