The NSE Nifty index also dipped 23.60 points, or 0.28 per cent, to end at 8,299.40.
Realty, Consumer Durables, Oil & Gas shares saw heavy selling while FMCG and healthcare stocks saw defensive buying, traders said.
After opening higher, the BSE Sensex hit a high of 27,670.19 on improved industrial production growth but lost all gains to end 159.54 points, or 0.58 per cent, lower at 27,425.73. Intra-day, it had dipped to 27,324.58 points.
Among 30-share Sensex, 21 constituents ended with losses and nine others finished higher.
Crude was dealt another blow Tuesday when key OPEC member the United Arab Emirates said the cartel could not stop world prices plunging and called for a cut in US shale oil output.
Brent crude for February delivery fell USD 45.50 a barrel -- around its lowest point since April 2009. On Monday, it had plunged more than five percent to end below USD 50.
Reviving hopes of manufacturing recovery, industrial production grew at five-month high of 3.8 per cent in November last year, but retail inflation inched up to 5 per cent in December.
Besides, participants preferred to book profits after recent gains, said Deepak Pahwa, a Delhi-based stock broker.
Bucking the trend, shares of Wipro, M&M, Cipla, Coal India, Dr Reddys, ITC Ltd, Axis Bank, Hindalco and Maruti Suzuki ended higher and cushioned the fall to some extent.
Globally, a mixed closing at Asian markets and a better opening in European markets also influenced trading here.
Sectorwise, BSE Oil & Gas index fell by 1.06 per cent, Realty index (1.85 pc), Consumer Durables index (1.20 pc), Power( 0.89 pc), Capital goods index (0.66 pc) and Banking index (0.55 pc) among others.
Meanwhile, foreigners bought shares worth a net Rs 244.95 crore yesterday as per provisional data.
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