Renewed fears about an earlier-than-expected US rate hike weighed on sentiment too, brokers said.
The 30-share BSE index resumed on a shaky wicket and continued to decline to hit a low of 27,614.32 as selling intensified before settling at 27,643.88, down 313.62 points, or 1.12 per cent.
The gauge had gained 148.15 points in the previous session on Friday.
Of the 30-share Sensex pack, 26 ended lower while ONGC, Bharti Airtel, Wipro and M&M advanced.
Investors who had been accumulating stocks in the past few sessions on hopes of a rate cut by the Reserve Bank of India were seen trimming positions after earnings numbers from some blue-chips failed to meet expectations of the Street.
Shares of diversified group ITC fell 3.29 per cent after its March quarter earnings did not cheer investors.
ITC on Friday reported a modest 3.65 per cent rise in standalone net profit at Rs 2,361.18 crore for the fourth quarter ended March 2015.
Other major losers were HDFC, Tata Steel, GAIL, Cipla, Tata Motors, SBI, Coal India, Dr Reddy's Lab, Hindalco, Axis Bank, L&T, Hind Unilever, Tata Power, Infosys, RIL, NTPC, TCS, Hero MotoCorp, ICICI Bank, Bajaj Auto, HDFC Bank and BHEL.
The broader markets too saw profit-booking by investors. The BSE smallcap index ended the day with a fall of 0.22 per cent while the midcap index was down 0.08 per cent.
Sector-wise, BSE metal index suffered the most by falling 1.70 per cent, followed by FMCG (1.62 per cent), capital goods (0.87 per cent), IT (0.74 per cent), banking (0.69 per cent), healthcare (0.60 per cent), realty (0.45 per cent), auto (0.28 per cent) and power (0.16 per cent).
Last Friday, foreign portfolio investors and domestic institutional investors (DIIs) net bought shares worth Rs 211.42 crore and Rs 237.62 crore, respectively, according to provisional stock exchange data.
