She held 2,45,89,250 shares accounting for 2.14 per cent of the total shareholding, the Bangalore-based firm said in a filing.
The promoters, comprising founders of Infosys and their family members, cumulatively hold 13.08 per cent stake in Infosys, it added.
Interestingly, N R Narayana Murthy's son Rohan Murty has the second largest holding with 1,58,99,564 shares or 1.38 per cent share in the firm.
Murty was often considered as a front-runner for the top job at Infosys. The speculations gained traction, especially after senior Murthy was last year brought back from retirement to the helm of affairs after the firm posted lacklustre results.
The Murthys together hold 3.44 per cent stake, while Nilekanis have 2.29 per cent shareholding in the company at the end of December 2014.
Narayana Murthy and Nandan Nilekani individually hold 0.38 per cent share and 0.93 per cent share, respectively.
In December last year, Infosys co-founders Naryana Murthy, Nandan Nilekani, Dinesh K and S D Shibulal's wife , Kumari Shibulal, along with their families, sold 32.6 million shares for an overall amount of Rs 6,484 crore.
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