The new cases were registered in the oil-rich province Deir Ezzor, the majority of which is controlled by the Islamic State group and where a siege of the capital has restricted access to basic goods for some of the population.
An outbreak hit the province in 2013-2014, when 36 cases were reported, according to the Polio Global Irradication Initiative.
WHO spokeswoman Sona Bari told AFP yesterday that the new cases are from a different strain of the virus.
"Circulating (vaccine-derived polioviruses) are extremely rare forms of poliovirus...That can emerge in under-immunised populations," it said in a statement.
"Although access to Deir-Ez-Zor is compromised due to insecurity, the Governorate has been partially reached by several vaccination campaigns against polio and other vaccine-preventable diseases since the beginning of 2016," the initiative said.
"Outbreak response plans are being finalized," it added.
A total of 402 such attacks - many of them fatal - were registered between November 2015 and December 2016, it said.
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