In his annual report to the United Nations Human Rights Council, Zeid Ra'ad Al Hussein said the government's actions in the area were "legally and morally unsustainable", while warning the next nightmare for Syrian civilians would inevitably arrive soon.
"This month, it is Eastern Ghouta which is, in the words of the Secretary General, hell on earth; next month or the month after, it will be somewhere else where people face an apocalypse - an apocalypse intended, planned and executed by individuals within the government, apparently with the full backing of some of their foreign supporters," Zeid told the council.
The Syrian army and allied militia launched an offensive on February 18 to retake Eastern Ghouta, the last rebel-controlled region near the capital Damascus.
The offensive has been backed by Russia, the government's key military ally.
They have since recaptured more than 40 percent of the area with support from a devastating bombing campaign that has killed more than 800 civilians.
By today, government troops were at the edges of several key towns, including Misraba, Beit Sawa, Jisreen and Hammuriyeh.
Beyond Eastern Ghouta, Zeid said the seven-year-old conflict in Syria was entering "a new phase of horror", noting rising violence in the rebel-held area of Idlib and Turkey's offensive in Afrin.
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