The attack on Tuesday in the Mawza district of the southwestern province of Taez killed at least 20 people, including four children, according to residents.
The UN human rights office, which put the death toll at 18, said the strikes hit three families who were staying in a makeshift straw house after being displaced from their homes three months ago by fighting.
The office said in a statement that the strike was carried out by "Arab Coalition Forces", referring to the Saudi-led alliance fighting Shiite rebels in support of Yemen's internationally recognised government.
The Saudi-led coalition has faced repeated criticism over civilian casualties in Yemen. It accuses the Iran-backed rebels of using civilians as human shields.
The coalition has admitted responsibility for some strikes that killed non-combatants, including a raid on the rebel-held capital Sanaa in October 2016 that killed more than 140 people at a funeral ceremony.
The United Nations called for a "comprehensive and impartial investigation" into the latest incident.
The conflict in Yemen has escalated dramatically since March 2015, when the Saudi-led forces launched a military operation against the rebels.
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