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Deficiencies in vitamin B12 and folate (vitamin B9) is linked with higher homocysteine levels in blood, which could be associated with a greater physical fatigue in men and decreased motivation in women, according to a study. "This suggested relationship between vitamin B12, folate, and fatigue in healthy individuals may represent the first report of its kind. Blood homocysteine levels have traditionally raised concerns in relation to cardiovascular disease, dementia, and fractures," lead researcher Hiroaki Kanouchi, from Osaka Metropolitan University in Japan, said. "However, our findings suggest that attention should also be paid to fatigue and motivation in the future," Kanouchi said. Fatigue that does not resolve with rest, and reduced motivation can impair one's daily functioning and quality of life. Chronic fatigue, in which exhaustion is severe and unexplained and can last for months, is linked to a reduced productivity at work and an elevated utilisation of healthcare. The
Health officials on Friday released the first nationally representative estimate of how many US adults have chronic fatigue syndrome: 3.3 million. The Centers for Disease Control and Prevention's number is larger than previous studies have suggested, and is likely boosted by some of the patients with long COVID. The condition clearly "is not a rare illness, said the CDC's Dr. Elizabeth Unger, one of the report's co-authors. Chronic fatigue is characterized by at least six months of severe exhaustion not helped by bed rest. Patients also report pain, brain fog and other symptoms that can get worse after exercise, work or other activity. There is no cure, and no blood test or scan to enable a quick diagnosis. Doctors have not been able to pin down a cause, although research suggests it is a body's prolonged overreaction to an infection or other jolt to the immune system. The condition rose to prominence nearly 40 years ago, when clusters of cases were reported in Incline Village, ...