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An advancing of chronic kidney disease may be linked to an increase in cognitive impairment, such as problems with attention, processing speed and executive function, according to a study. The findings, published in The Journal of the American Medical Association (JAMA) Network Open, underscores that severity of chronic kidney disease could be a risk factor for cognitive decline. Chronic kidney disease is a long-term, progressive loss of kidney function -- where kidneys are not able to purify blood -- often lasting more than three months. Researchers, including those from Tulane University in the US, examined over 5,600 participants aged 21-79, analysing blood and urine samples for kidney function, and a cognitive function assessment for brain function over six years. "In this cohort study of 5,607 participants with CKD (chronic kidney disease), a higher urinary protein to creatinine ratio (in a urine test) was associated with impairments in attention and processing speed as well
Neurological conditions such as epilepsy, Alzheimer's disease and dementia are now the leading cause of ill health and disability globally, affecting 3.4 billion people in 2021, according to a major new analysis published in The Lancet Neurology journal. Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years. This is due to the growth and ageing of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors, the researchers said. The study suggests that worldwide, the overall amount of disability, illness, and premature death -- a measurement known as disability-adjusted life years (DALYs) -- caused by neurological conditions increased by 18 per cent over the past 31 years, rising from around 375 million years of healthy life lost in 1990 to 443 million years in 2021. The analysis from the .