"My friend's son was born with EB," the actress said.
"I've been a part of it since then. He's 11 now. There is no cure for this disease. It's just such a horrible thing."
The condition, which usually strikes babies and children, causes painful skin blisters; there is little hope for those affected beyond the age of 30, reported People magazine.
"You have no choice to feel for these kids," said Cox, 51, who has an 11-year-old daughter, Coco.
"The disease is very rare so need to bring awareness.
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