However, all other Indians in the fray lost their respective second round matches to bow out of the competition.
The world number two Indian took a little more than an hour to pack off the Japanese 16-21 21-16 21-9 at the Singapore Indoor Stadium.
The 23-year-old from Hyderabad will next take on Lindaweni Fanetri of Indonesia in the last-eight stage.
Both Saina and Hirose started on equal footing in the opening game and it was a neck-and-neck battle till 14-14 before the Japanese girl opened up a slender two-point lead.
Saina bounced back in the second game and surged ahead to 4-1 but Hirose clawed back with five straight points and opened up a 6-4 lead.
Thereafter though, the game was seen tilting from one end to another and the two were tied at 12-12. Saina then successfully broke free and eventually moved up to 20-16 before taking the match to the decider.
The third game was a cakewalk for Saina as her opponent ran out of steam to let the Indian register an easy win.
Sai Praneeth, who had stunned world No 4 Yun Hu of Hong Kong in his opening round match, could not repeat yesterday's performance as he lost in a contest that lasted 53 minutes.
India's campaign also ended in both mixed doubles and men's doubles events.
While the men's doubles pair of Pranaav Jerry Chopra and Akshay Dewalkar lost to the sixth seeded Korean duo of Baek Choel Shin and Yeon Seong Yoo 14-21 19-21 in 33 minutes, Arun Vishnu and Aparna Balan were outplayed by Indonesians Praveen Jordan and Vita Marissa 10-21 18-21 in just 27 minutes in the mixed doubles.
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