Besides, monthly expiry in the derivatives segment also weighed on the sentiment.
The 30-share barometer, which had lost over 726 points in the past four sessions, fell further by 196.27 points, or 0.95 per cent, to 20,451.03.
All the sectoral indices were trading in negative zone, led by consumer durables, realty and banking.
Similarly, the wide-based National Stock Exchange index Nifty fell by 52.50 points, or 0.86 per cent, to 6,067.50.
They said participants adopted a cautious approach keeping in view the monthly expiry in the derivatives segments.
In the Asian region, Japan's Nikkei Index tumbled 3.33 per cent, while Hong Kong's Hang Seng index shed 1.22 per cent in early trade.
The US Dow Jones Industrial Average ended 1.19 per cent down in yesterday's trade.
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