'Smart' bandage to speed up wound healing

Researchers are developing a 'smart' bandage that can draw bacteria out of wounds and speed up the healing process.
Scientists at Swinburne University of Technology in Australia have used a technique called electrospinning - in which polymer filaments 100 times thinner than a human hair are squeezed out of an electrified nozzle - to develop nanofibre meshes that can draw bacteria from a wound.
In the first phase of research polymer nanofibres were placed over the top of films of Staphylococcus aureus, a bacterium involved in chronic wound infection. The researchers found the bacteria quickly attached to the fibres.
When the fibres were smaller than the individual bacteria, fewer cells attached and those that did attach died as they attempted to wrap around the fibre.

In the second phase, the tiny nanofibres were coated with different compounds and tested on the bacteria Escherichia coli, also commonly found in chronic wounds.
The researchers found these bacteria rapidly transferred onto fibres coated with allylamine, independent of the fibre size, but did not attach to fibres coated with acrylic acid.

In the third phase of research, the nanofibre meshes have been tested on tissue-engineered skin models in a partnership with researchers at the University of Sheffield in the UK.
"For most people, wounds heal quickly. But for some people, the repair process gets stuck and so wounds take much longer to heal. This makes them vulnerable to infection," said Swinburne PhD candidate Martina Abrigo.

"We hope this work will lead to smart wound dressings that could prevent infections. Doctors could put a nanomesh dressing on a wound and simply peel it off to get rid of the germs," she said.