The study offers hope that social media can become an early warning system to help prevent suicides, researchers said.
Researchers at Brigham Young University examined tweets originating from 50 US states over a three month period.
Sifting through millions of tweets, their algorithms searched for direct discussion of suicide, as well as keywords and phrases associated with known risk factors such as bullying.
"With social media, kids sometimes say things that they aren't saying out loud to an adult or friend in person," said Christophe Giraud-Carrier, a BYU computer scientist and one of the study's seven authors.
Each state's ratio of suicidal tweets strongly correlated with its actual suicide rate.
In Alaska, which has the country's highest suicide rates, researchers identified 61 Twitter users as at-risk individuals.
In Texas, where the rate of suicide is slightly lower but the population is significantly higher, more than 3,000 Twitter users were flagged as at-risk cases. In Utah, the study found 195 Twitter users who may be at risk.
"Somebody ought to do something. How about using social media as a complement to what is already done for suicide prevention?," Giraud-Carrier said.
"Tweets may be useful to address some of the functions that suicide hotline groups perform, but at the discretion and potential for such organisations to provide those services via Twitter," said Michael Barnes, a health science professor at BYU and a study co-author.
Previous research found that about 15 per cent of tweets contain at least state-level location information, suggesting that state health departments in US might also play a role.
"Suicide is preventable. Social media is one channel for monitoring those at risk for suicide and potentially doing something about it," said Carl Hanson, a BYU health scientist and study co-author.
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