Maduro said yesterday he instructed Foreign Minister Elias Jaua to throw out the diplomats.
"The officials have 48 hours to leave the country. ... Yankees go home," the leftist leader said in a public address.
Maduro named the diplomats but did not disclose which posts they are holding. A US embassy official contacted by AFP was unable to confirm if they worked there.
The president said the diplomats had met with the "Venezuelan far-right" -- as he calls the opposition -- to finance his opponents and "encourage actions to sabotage the power system and the economy."
Earlier this month, Maduro blamed the opposition for causing a major power breakdown that affected much of the country.
"The actions of the government of Barack Obama do not matter," Maduro said, accusing the US president of fomenting sabotage.
"We will not allow an imperial government to bring money and see how they can stop basic companies and stop the electricity to turn off all of Venezuela."
Maduro had expelled two US military attaches on March 5, hours before announcing the death of president Hugo Chavez, accusing them of promoting "destabilisation projects."
