Fatty Liver Cirrhosis

Novo Nordisk India on Friday said it has received approval from the Central Drugs Standard Control Organisation for indication of its Wegovy injection for the treatment of fatty liver disease in India. The Central Drugs Standard Control Organisation (CDSCO) has approved a new indication for Wegovy (semaglutide injection 2.4 mg), Novo Nordisk India said in a statement. It makes Wegovy the first and only GLP-1 RA to be approved both globally and in India for the treatment of noncirrhotic Metabolic Dysfunction Associated Steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis along with a reduced calorie diet and increased physical activity, it added. MASH is a liver disease that develops due to excess fat buildup in the liver, causing chronic inflammation and liver damage. Novo Nordisk India MD Vikrant Shrotriya said the burden of MASH continues to rise in India, but treatment options are still severely limited. People with MASH face a higher risk of serious liver .

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More than three of every five liver cancer cases in the world can be prevented by addressing risk factors, such as hepatitis, alcohol habits and non-alcoholic fatty liver conditions, according to an analysis report of The Lancet Commission on the fatal disease. Researchers from The Hong Kong Cancer Institute, Fudan University, and others in China, South Korea, the US and Europe authored the report. The team predicted a 35 per cent increase in liver cancer driven by a severe form of metabolic dysfunction-associated steatotic liver disease that is caused by excess fat in the liver and called metabolic dysfunction-associated steatohepatitis. Liver cancer is among the top three types of cancer deaths in 46 countries, according to a 2022 study published in the Journal of Hepatology. The Lancet Commission's findings present a huge opportunity for countries to target risk factors such as viral hepatitis, alcohol and obesity to prevent liver cancer and save lives, said first author Stephen

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Amid a rise in liver diseases among both urban and rural populations, doctors on Friday emphasised the critical link between dietary habits and liver health. On the eve of World Liver Day, medical experts are sending the message of "Food is Medicine", saying healthy changes today can cut the risk of liver disease by 50 per cent. Liver Transplantation Society of India president Dr Sanjiv Saigal said, "Damage done to the liver from poor dietary choices, alcohol, processed food and sedentary lifestyles can be reversed if we take action today." The liver has a remarkable ability to heal itself and even years of damage can be reversed with the right lifestyle changes, he added. A diet rich in fresh fruits, green vegetables, whole grains and lean protein not only prevents liver disease but also supports liver regeneration. "As doctors, we witness miracles when patients switch to cleaner diets -- liver enzyme levels improve, energy levels bounce back and long-term health outcomes become

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