Without whole-genome sequencing, a treatable TB epidemic is a challenge

HaystackAnalytics, an IIT Bombay-incubated company working in the area of genomics using big data has created a comprehensive drug resistance test for tuberculosis (TB). In an emailed interview with Sohini Das, Dr Chaitali Nikam, Director-infexn, HaystackAnalytics, explains why whole-genome sequencing is critical for eliminating TB from India. Edited excerpts.
 

Why is whole-genome Sequencing (WGS) critical for tackling the TB crisis in India?

TB is not only a global public health concern, with an estimated 10 million people suffering from the disease and 1.4 million people having died in 2019, but it also has societal consequences. India has the highest TB