A senior district police officer said Sabir Ali and Shankar Saha were picked up from the town today and were being interrogated by a CID team.
Meanwhile, forensic experts today visited the residence and collected samples as police sealed off entry points to the house.
Top police officials, including Additional Director General, North Bengal, were present there along with the forensic team.
Most of the business establishments in the town downed their shutters today in response to a 'byabsa bandh' called by Malda Merchant of Chambers and Commerce.
While the couple was found in their bedroom, their caretaker was found outside the main building.
The couple's children were not at home at the time of the incident as they study in institutions outside Malda.
The miscreants had looted the house before escaping, police had said.
