The quake's epicentre was located near Jurm in northeast Afghanistan, 250 kilometres from Kabul and at a depth of 213.5 kms, according to the US Geological Survey.
Six people, including children, were killed in Swat, while four people were killed in the Bajaur tribal region after the collapse of buildings in the area.
An eight-year-old child was killed in Kallar Kahar, whereas one casualty was also reported from Kasur after the roof of a house collapsed.
At least 194 injured were brought to Swat's Saidu Sharif Teaching Hospital, which does not have adequate medical facilities.
More than 100 wounded have been admitted to Peshawar's Lady Reading Hospital.
Tremors were also felt in major cities, including Karachi, Lahore, Islamabad, Rawalpindi, Peshawar, Quetta, Kohat and Malakand.
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