Bosses at XS Las Vegas and Encore Beach Club confirmed the news via Twitter, citing "personal reasons".
Representatives for the "Wake Me Up" hitmaker have also confirmed the cancellations, insisting that other tour dates would not be affected.
"Due to personal reasons @Avicii has cancelled all his 2016 dates," a message from Encore Beach Club reads.
"As a result we are pleased to announce that @DillonFrancis will be his replacement this Saturday."
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