The bomb was planted on the bicycle parked on a market street in Chaman town, close to the Afghan border, police said.
The intensity of the blast destroyed four vehicles situated in the vicinity and also damaged more than a dozen shops. Windowpanes of nearby buildings also shattered due to the high intensity of the blast, Dawn reported.
Those injured in the blast were shifted to District Headquarters Hospital Chaman, where one of them succumbed to his wounds.
No on has claimed responsibility for the attack.
Chaman town is one of the two main crossing points for supplies for American and NATO troops fighting Taliban in Afghanistan.
Baluchistan, Pakistan's largest but least developed and most sparsely populated province, has been racked for decades by a separatist insurgency that was revived in 2004.
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