Researchers at the University of Auckland found that birth order may affect the risk of cardiovascular disease and type 2 diabetes.
The study of middle-aged men living in New Zealand found that kids born first into their family were about 7kg heavier and had a bigger BMI than second-borns, 'BBC News' reported.
They also had more insulin resistance, which can lead to health problems, researchers said.
There is some evidence to suggest birth order may influence the body's fat make-up and metabolism, from infancy to the teenage years. However, the potential impact in mid-life is unknown, researchers said.
"First-born men were heavier and had lower insulin sensitivity than second-borns," researchers said.
"Thus, first-born adults may be at a greater risk of metabolic and cardiovascular diseases," they added.
Researchers cautioned that larger studies are needed to fully evaluate this link.
The study was published in the journal Scientific Reports.
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