The 27-year-old from Florida fired a five-under-par final round 67 to finish on 16 under for the tournament following a tense duel with compatriot Brian Harman that was settled on the home stretch at the rural Wisconsin course.
Koepka's 16-under-par total equalled the record for the lowest winning under par total at a US Open set by Rory McIlroy at the 2011 championship.
Third round leader Brian Harman, who had led by one-shot at the start of the round, finished second on 12 under after an even-par 72. He tied with Japanese world number four Hideki Matsuyama who shot a superb six-under-par 66.
Harman and Koepka spent much of the round locked at the top of the leaderboard.
But the turning point in a gripping war of nerves came just after the turn when Harman struggled through back-to-back bogeys on the 12th and 13th.
- Birdie hat-trick -
====================
World number 22 Koepka then uncorked a brilliant trio of birdies on the 14th, 15th and 16th holes to surge into a four-shot lead and virtually assure himself of the title.
Koepka's win extended a remarkable run of victories by players who had never previously won a major. Since Jason Day lifted the 2015 PGA Championship, every major championship has been won by a first-timer.
With strong winds buffeting the 7,721-yard layout at Erin Hills earlier in the day, Mother Nature had appeared poised to bite back after three days of benign conditions which led to a feast of low-scoring.
But with the gusts gradually weakening over the course of the afternoon, Koepka and Harman picked up where they left on Saturday, seamlessly getting into the groove early on to jump ahead of the field.
- War of nerves -
=================
Harman, playing in the final pairing immediately behind Koepka, then rolled in a 29-foot birdie putt on the third to join Koepka at the top of the leaderboard.
As the front nine progressed, it looked increasingly as if it would come down to a question of who would blink first.
Koepka landed the first blow on the par-four eighth, draining a magnificent 33ft putt to move one clear at 14 under.
Koepka then missed a golden chance to regain the lead on the 11th, but was unable to convert a nervy nine-foot putt for birdie.
Another birdie chance lipped out on the 12th as the tension mounted.
The deadlock was broken when Harman's tee-shot on the 12th landed into the deep fescue, forcing him to hack out onto the fairway. Unable to get up and down Harman bogeyed to leave Koepka clear on 13 under.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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