The spikes in Indiana, Kentucky, Ohio and West Virginia over the past few days have seen rescue workers rushing from scene to scene to provide overdose antidote drugs.
While it's unclear if one dealer or batch is responsible for the multistate outbreak, the spikes reflect the potency of heroin flooding the Midwest.
In Cincinnati, police today asked for the public's help in identifying the source of the heroin behind an estimated 78 overdoses in two days.
Emergency rooms estimate they had 174 suspected opioid overdose cases this week, including three deaths. Last year, accidental drug overdoses killed 3,050 people in Ohio, an average of eight per day, state officials said.
A record high 47,055 people died from drug overdoses in the United States in 2014, according to the latest figures from the Centers for Disease Control and Prevention. That was up 7 percent from the year before, spurred by large increases in heroin and opioid painkiller deaths.
In Ohio alone, emergency medical personnel last year administered nearly 19,800 doses of naloxone, known by the brand name Narcan.
In Mount Sterling, Kentucky, one person died following a series of 12 heroin overdoses that occurred within hours of each other on Wednesday. Most of the victims were in their 30s or 40s, said Jeff Jackson, battalion chief for the Montgomery County Fire Department.
In Huntington, West Virginia, an Ohio man was charged with heroin distribution in connection with 27 drug overdoses in a few hours last week, a federal prosecutor said today.
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