The Dutch anti-fraud agency FIOD "is leading, under the direction of the Dutch prosecution service, an inquiry into ING Bank NV," Marieke van der Molen, spokeswoman for the prosecutors, said.
"The bank is suspected of not having notified, or not having notified early enough, unusual transactions," she told AFP.
Among suspect payments are funds from Russian telecoms company VimpelCom to an Uzbek civil servant.
The Dutch daily Financieele Dagblad said investigators are probing what role the Amsterdam-based banking and insurance multinational may have had in the payment of possible bribes.
ING spokesman Raymond Vermeulen said: "These investigations concern the compliance with various requirements related to the on-boarding of clients, transaction screening and reporting of suspicious activities, all to prevent the facilitating of money laundering and corrupt practices."
The bank was cooperating "with the investigations," he said, but adding he could not comment further as the matter was under investigation.
In its annual report released last week, ING said it has "also received related information requests from US authorities".
In 2012, ING agreed to pay a record USD 619 million to the US authorities to settle accusations that it had violated American sanctions banning transactions with Cuba, Iran, Myanmar and Sudan.
ING has over 52,000 employees and customers in over 40 countries.
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