ECB president Mario Draghi was scheduled to explain the reasoning behind the decision at his traditional post-meeting press conference.
Central bank watchers expected him to leave the door open to further monetary easing given signs that eurozone inflation is still much lower than the ECB would like.
"The decision to leave its policy stance unchanged was widely expected, but Draghi is likely to give some dovish signals," said Capital Economics economist Jonathan Loynes.
"Admittedly, the latest news on the eurozone economy has been reasonably upbeat ... (and) the Greek crisis has clearly eased somewhat after the approval of the third bailout.
"Nonetheless, the growth outlook is hardly strong and the concerns over China and the appreciation of the euro present a serious external threat," the expert said.
Area-wide inflation was uncomfortably close to zero and could well drop below it again in coming months if oil prices remain at the current level, Loynes argued.
"Against that background, we suspect that Draghi will insist again that the ECB's current QE programme will be implemented in full and give a further strong hint that it might be extended or accelerated, or both. He won't say so, but part of the intention will no doubt be to weaken the euro again," the analyst said.
The International Monetary Fund on Wednesday insisted that global central banks must ensure that monetary conditions remain "accommodative to prevent real interest rates from rising prematurely."
And addressing the ECB directly, it said the QE programme had "improved confidence and financial conditions, and raised inflation expectations initially.
"More recently however, inflation expectations have reversed, and the euro has strengthened, which could put downward pressure on prices. Hence, the programme should be extended if there is not sufficient improvement in inflation consistent with meeting medium-term price stability objectives," it said.
Fears of deflation -- a dangerous spiral of falling prices -- persuaded the ECB to launch in March its controversial QE programme, under which it plans to purchase 60 billion euros (USD 68 billion) of sovereign bonds each month until September 2016, or 1.14 trillion euros in all.
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