Jermaine Blackwood's maiden Test hundred lifted the home side to 295 in their first innings with James Tredwell's off-spin bringing him the excellent figures of four for 47 off 26 overs and ensuring his side earned a significant first innings lead.
Left with the final session to build on an advantage of 104 runs, openers Jonathan Trott and captain Alastair Cook were prised out in double-quick time by Jerome Taylor.
Defending a first innings total of 399, English perseverance in the field on another sweltering day's play eventually paid off.
Tredwell made the important breakthrough in the morning by removing Shivnarine Chanderpaul for 46 before adding the wickets of Jason Holder and Kemar Roach as the West Indies lower order failed to show any meaningful resistance, the last four wickets subsiding for 19 runs.
Reprieved when he offered a slip catch off a no-ball delivered by Ben Stokes on the second evening, the 23-year-old Jamaican benefited from another let-off half-an-hour into the day's play when on 43 as Tredwell failed on hold to a difficult chance diving to his left at gully.
Stokes was the suffering bowler yet again, and his disappointment intensified when the same batsman survived a confident lbw appeal and subsequent referral to the television umpire before edging a boundary between the two slip fielders early in the afternoon session.
"It's a very big difference," Blackwood observed at the end of the day in commenting on the significance of getting to a Test hundred after three previous half-centuries.
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