Fortune said nearly half the women on 'The Most PowerfulWomen in Business 2014' list run huge companies, which is a record and "all are working hard to transform their businesses."
Nooyi, 58, dropped from the second position she held last year to third.
Fortune said her innovation push is paying off at PepsiCo,which has increased research and development spending by 25 per cent since 2011.
"In July the company raised its profit growth forecast for the year, which should help Nooyi counter calls by activist investor Nelson Peltz to break up the food and beverage giant," the publication said.
Topping the list for the third time is Rometty, whose strategy of investing in new technologies is showing results.
Even though IBM's revenue declined for the second consecutive year, falling nearly 5 per cent to USD 99.8 billion in fiscal 2013, its revenue rose 69 per cent for each division last year.
Rometty has also pledged to invest USD 1 billion in the development and commercialisation of the cognitive computing system, another future growth area for the company.
Making a huge jump in the rankings is General Motors CEO Mary Barra, who is ranked second this year up from the 29th position last year.
Barra became the auto industry's first female CEO in January and promptly faced GM's largest vehicle recall ever, 29 million so far from a faulty ignition switch linked to at least 13 deaths since 2005.
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