They discovered that DNA was different for gay and straight men around two genes: SLITRK5 and SLITRK6.
The study, published in the journal Scientific Reports, is the first to look at the complete genome of over 1,000 homosexual men and compare it to genetic data from 1,231 heterosexual males.
SLITRK6 is an important gene for brain development and is particularly active in the brain region which includes the hypothalamus.
The hypothalamus is crucial for producing hormones linked to control sex drive. Previous studies have shown that parts of it are up to 34 per cent larger in gay men.
"Because sexuality is an essential part of human life
for individuals and society it is important to understand the development and expression of human sexual orientation," said Alan Sanders, from NSUHS.
"The goal of this study was to search for genetic underpinnings of male sexual orientation, and thus ultimately increase our knowledge of biological mechanisms underlying sexual orientation," Sanders said.
However, experts suggest that the number of participants in the study is too small to draw population-wide conclusions, and the findings are not statistically significant.
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