England or Spain are lurking in pot two as potential group-stage opponents for the world champions in Friday's draw at Moscow.
Loew talked about the 2018 finals as being "the hardest tournament so far" of his 12-year reign in charge, because the Germans will be the team to beat.
"I am completely relaxed and don't have any sleepless nights," insisted Loew after a 2-2 draw against France in their final friendly of 2017 a fortnight ago.
"We have worked on building an incredibly good base. We know what we can do, so I am not nervous anymore about our preparations," he added.
Loew's goal is to arrive in Russia with every position covered, but he needs key players to return from injury and to find understudies for wing-backs Jonas Hector and Joshua Kimmich.
Borussia Dortmund playmaker Marco Reus has been out since May with a knee injury, while captain and goalkeeper Manuel Neuer is not expected back until January at the earliest after fracturing his foot.
- Midfield options -
====================
However, he is not short of options, especially in midfield.
Manchester City's Ilkay Gundogan is back fit after a serious knee injury while Mario Goetze, whose extra-time goal won the final three years ago, is shining in a struggling Dortmund team after recovering from a metabolic disorder.
Loew's gamble to rest all of his 2014 stars and take an inexperienced squad to the Confederations Cup in Russia earlier this year paid off when they beat Chile 1-0 to win the tournament.
Timo Werner proved himself as a fleet-footed striker with great finishing, ending Germany's wait for a replacement for Miroslav Klose.
The World Cup's all-time top-scorer with 16 goals retired from international duty after Brazil, and will carry the trophy onto the stage for the draw.
The Germans cruised through qualifying with 10 wins, and Loew has secured tough opponents for friendlies next March, against Spain in Duesseldorf and Brazil in Berlin, to further test his plans.
This will be his last chance to look at potential combinations before the squad is announced in May and by his own admission, Germany are not yet firing on all cylinders.
Only a last-gasp equaliser from Stindl rescued another draw with France in Cologne.
"Even after this outstanding year, our game still needs to click, things need to become automatic," said Loew.
It is still unclear where the Germans will be based for the World Cup, the main options being Moscow and Sochi.
Team manager Oliver Bierhoff preaches the practicalities of Moscow, the main hub for flights around the world's biggest country.
However, the players raved about the benefits of Sochi's beach and sea-air when they were based on the Black Sea for the Confederations Cup.
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