After analysing data from nearly 5,000 American adults, University of Michigan Health System researchers found that the quality of a person's relationships with a spouse, family and friends predicted the likelihood of major depression disorder in the future, regardless of how frequently their social interactions took place.
Individuals with strained and unsupportive spouses were significantly more likely to develop depression, whereas those without a spouse were at no increased risk.
And those with the lowest quality relationships had more than double the risk of depression than those with the best relationships.
Nearly 16 per cent of Americans experience major depression disorder at some point in their lives, and the condition can increase the risk for and worsen conditions like coronary artery disease, stroke and cancer.
"Our study shows that the quality of social relationships is a significant risk factor for major depression," said psychiatrist Alan Teo, study's lead author.
"This is the first time that a study has identified this link in the general population," said Teo.
Social strain and a lack of support - especially in spousal relationships and to some extent with family members - were both risk factors for developing depression later.
"These results tell us that health care providers need to remember that patients' relationships with their loved ones likely play a central role in their medical care," Teo said.
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