The IIT Guwahati team was awarded an incubation prize of Rs 10 lakh, an official statement said.
As a part of the competition, students were required to create a concept for the country in the field of healthcare, energy or transportation.
The winning team's project proposes wireless EEG (Electroencephalography) for monitoring of autistic patients. The EEG signals will be transferred through wireless means while the patient is at home.
A team from Vellore Institute of Technology was chosen as the runner-up with an incubation prize of Rs 5 lakh.
The GE Edison Challenge was first launched in 2008 with the aim of finding the best scientific and engineering talent.