"Oxytocin has actions in the brain and the ear that may help in tinnitus treatment and provide immediate relief," said lead researcher Andreia Azevedo from the Universidade Federal de Sao Paulo in Brazil.
Researchers randomly assigned 17 people with tinnitus, average age 63, to puffs of oxytocin or a placebo (distilled water) in each nostril.
The study volunteers were asked to assess their symptoms 30 minutes after treatment, and then again, 24 hours later.
However, it is not clear how oxytocin works to relieve tinnitus, 'Health Day' reported.
She speculated that it may have an effect in the ear, probably related to fluid regulation in the inner ear, and a brain effect that may be related to the production of the neurotransmitter dopamine.
"For some patients, tinnitus disappeared or reached a non-distress level," Azevedo said.
"As usual in tinnitus treatment, in some patients the tinnitus kept low, and for some it raised after drug therapy ended," she said.
"We did not have any side effects, but further larger studies are necessary to establish the role of oxytocin in tinnitus treatment," she added.
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