The attacks in North Waziristan, a militant stronghold on the Afghan border, destroyed hundreds of shops and houses, officials said.
They came a day after air strikes and ground fighting killed at least 71 suspected militants and four security personnel in the same area.
Local residents and officials said thousands had started fleeing towards the garrison town of Bannu in neighbouring Khyber Pakhtunkhwa due to the unrest.
Intelligence officials told AFP that the bodies of two people killed in Thursday's action had so far been recovered, but the full death toll may only come to light after the fighting has ended.
Troops backed by tanks, helicopter gunships and reconnaissance drones swung into action today, destroying shops and houses, local residents and officials said.
The official said a curfew had been imposed in the whole of North Waziristan.
"Artillery and helicopter gunships are targeting militant hideouts," a local intelligence official in Miranshah, the main town of North Waziristan, told AFP.
He added that troops on the ground had begun a door to door search operation for militants.
An official statement from the army said a military camp in Miranshah had come under attack from insurgents, who were successuly repelled.
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