The second-in-line to Britain's throne will face emergencies ranging from traffic accidents to heart attacks in his role working for East Anglian Air Ambulance.
William will juggle his royal duties with nine-and-a-half hour shifts in the first few months, as part of a rotation where he will work four days and then have four days off.
He'll work less in the future to accommodate royal tasks.
"I feel doing a job like this really helps me to be grounded and that's the core of what I'm trying to become," he said. "I'm trying to be a good guy, to do what I can and trying to be a decent individual."
"At the same time, there is a lot of responsibility, especially when George is around - he's been a little monkey," he said. "It's no more difficult than what everyone else has to do."
William and his crewmates began work right way, responding to a first emergency call at 9:20 a.M. (0820 GMT, 4:20 am EDT). The charity plans to release details of the incident later today.
