No casualties have been reported so far.
The epicenter of the quake was detected at a depth of 10 km, the China Earthquake Networks Centre said.
The earthquake damaged 51 houses and affected 1,508 people, who have relocated to their relatives' homes, the local government sites and clinics, said Atux mayor Ababakeri Mametmin, state-run Xinhua news agency reported.
Tents, stoves and other relief materials have arrived at the affected areas, he said.
The Kizilsu prefecture is located in the west-end of Xinjiang.
Some old houses were "moderately damaged" by the tremor, according to the regional seismological bureau.
Zhi Hao, secretary of the ruling Communist Party of China, (CPC) in Karajol, said 17,499 people live in the township, which covers an area of 8,452 square kilometres.
The scattered settlement of many herdsmen has created difficulties for casualty and damage counting and rescue efforts.
The regional government has sent a work team to the affected areas.
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