Eastern Ghouta, one of the last remaining opposition strongholds in Syria, is among four so-called "de-escalation zones" set up earlier this year under a deal agreed by regime allies Russia and Iran, and rebel supporter Turkey.
But despite the deal, violence has spiralled in the area in recent days.
Today, air strikes and artillery fire on several parts of Eastern Ghouta killed at least 18 civilians, the Britain-based monitor Syrian Observatory for Human Rights said.
At a field clinic in the city of Douma, which has regularly come under government attack, medics worked with the limited supplies available to them to treat waves of arriving injured.
The wails of a distraught mother could be heard along with the low moans of a wounded man who rocked back and forth in pain on a white hospital bed.
A young boy waited to be treated, the leg of one trouser pulled up to reveal a bloodied wound on his left shin.
Elsewhere, some of the bodies of those who could not be saved were wrapped in light blue sheets tied with white strips of fabric at the ankles, waist and head.
Others who had yet to be wrapped up were still lying on a bloodied tile floor in another part of the clinic, where one man wept openly, his left hand bandaged.
The deaths come a day after at least 23 civilians were killed in the region in regime air strikes and artillery fire, among them four children.
Rebels have also fired from the area into Damascus in deadly attacks of a kind rarely seen in the capital.
Eastern Ghouta is already in the grip of a humanitarian crisis caused by a crushing regime siege of the area since 2013 that has caused severe food and medical shortages.
Humanitarian access to Eastern Ghouta has remained limited despite the implementation of the ceasefire zone, and a United Nations official has named the region as the "epicentre of suffering" in Syria.
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