Sergey Lavrov made the remarks today on a visit to Greece, a NATO and European Union member that has maintained close ties with Russia.
He didn't name any countries. Peace talks have involved US Secretary of State John Kerry and the foreign ministers of Turkey, Saudi Arabia, Qatar, and Iran.
"Unfortunately on many occasions, efforts for a political resolution have been sabotaged. That is not in accordance with UN Security Council resolutions . Some parties are backing extremists aimed at removing the Assad regime," Lavrov said.
Over the weekend, the Russian navy destroyer Smetlivy reached Greece's main port of Piraeus before sailing onto the east Mediterranean to join warships backing government forces in Syria's five-year-old civil war.
Russia's relations with the US and its allies came under further strain after Moscow used airpower to back a Syrian government siege of Aleppo, Syria's second largest city. Peace talks resumed after Russia halted the airstrikes last month.
Athens is keen to maintain close ties with fellow-Orthodox Christian Russia, despite its participation in EU sanctions against Moscow, and a gas pipeline project designed to limit Russia's regional energy dominance.
Russia is one of Greece's main trading partners, but business has been hit by the sanctions and a drop in commodity prices.
Lavrov's trip comes less than two weeks before a visit to Greece by President Barack Obama.
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