The 30-share barometer fell by 30.26 points, or 0.11 per cent, to 25,850.51 with power, capital goods, realty, consumer durables and banking sector stocks leading the fall.
The index had gained 551.63 points in the previous two sessions.
Similarly, the National Stock Exchange index Nifty moved down by 15.25 points, or 0.19 per cent, to 7,711.80.
Brokers said selling activity emerged largely on disappointing economic data as country's industrial production slowed to 3.4 per cent in June as against 5 per cent in May.
Among other Asian markets, Hong Kong's Hang Seng index was down by 0.09 per cent, while Japan's Nikkei moved up by 0.16 per cent in early trade.
The US Dow Jones Industrial Average ended 0.06 per cent lower in yesterday's trade.
