Mohammed Alloush, a leading member of the powerful Army of Islam rebel group, told journalists that those pressing to form a unity government with regime members were "delusional."
"Whoever wants us to go into a unity government with these thugs who kill children is delusional," he said, minutes before heading into a meeting with the main opposition grouping, the High Negotiations Committee (HNC).
The HNC was in internal talks today morning to discuss its next steps, after a similar and tense meeting the previous evening, an opposition source said.
"The problem is not with (UN envoy Staffan) de Mistura. The problem is with the criminal regime that decimates children and with Russia which always tries to stand alongside criminals," Alloush said.
His appointment as chief negotiator has been controversial. Syria's government and Russia regularly refer to the Army of Islam as "terrorists."
Alloush, a stocky man in his 40s, also said Kurdish forces fighting jihadists in northeast Syria were "a branch of the regime."
HNC head and former Syrian prime minister Riad Hijab is set to arrive in Switzerland today, an HNC spokesman said, in a potential sign of fresh momentum after talks faltered yesterday.
The UN-brokered talks in the Swiss city are aimed at ending Syria's war, which has killed more than 260,000 people.
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