On Wednesday of last week, NASA learned that a faulty valve had interfered with the cooling loops that regulate equipment temperature aboard the orbiting space lab.
The six-man crew was never in danger due to the problem, but NASA has said it would like the system fixed for good, and soon.
As anticipation built and the hours ticked down, Orbital Sciences rolled its Antares rocket out to the launch pad at Wallops Island, Virginia in preparation for a Thursday launch of its Cygnus supply ship at 0749 IST.
A US space agency spokesman told AFP a final decision could come later today or early tomorrow.
"We are trying to figure out all the details we need to make a good decision," NASA spokesman Kelly Humphries said.
At some point, multiple spacewalks will be needed to fix the problem. But in recent days, engineers have reported some success in manipulating the system from the ground.
If the agency decides its temporary fix -- which has involved the shutting down of some equipment -- is stable, the Orbital launch could go ahead on Thursday.
The company did a demonstration launch and berthing at the ISS in September, showing it was capable of the mission and paving the way for more supply trips.
When NASA lost its capacity to reach space with the retirement of the 30-year shuttle program in 2011, Orbital Sciences and SpaceX stepped in to fill the void with their privately-made supply spacecraft.
Both companies have lucrative contracts with the US space agency to ferry supplies to the ISS.
Orbital has a USD 1.9 billion contract with NASA for eight cargo missions to the ISS, toting supplies, food, science experiments and spare parts.
If NASA decides that engineers on the ground have not been able to fix the ISS cooling system in a way that would be stable for the coming weeks, the Orbital launch would be delayed until next year.
The first of a series of spacewalks by the astronauts at the ISS would then begin later this week.
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