US Assistant Secretary of State Victoria Nuland and top Kremlin aide Vladislav Surkov met near the city of Kaliningrad in Russia's exclave bordering European Union members Lithuania and Poland, a source familiar with the situation told AFP.
"The meeting is closed to the media. The topic is Ukraine," the source said.
The meeting took place in Russia because Surkov is subject to Western sanctions over the Kremlin's role in the Ukraine crisis and is unable to travel to the EU, the source said.
"Assistant Secretary Nuland's meeting with presidential advisor Surkov is part of our continued efforts to work with Russia to ensure full implementation of the Minsk agreements, in close coordination with the other Normandy powers -- Ukraine, Germany, and France," Kirby said in a statement.
No other details were immediately released.
The meeting came after Russian President Vladimir Putin and US President Barack Obama discussed the Ukraine crisis by phone earlier this week.
Putin for his part said the Ukrainian authorities must establish "direct dialogue" with separatists in the east and agree constitutional amendments with them.
The meeting came amid an apparent international push to shore up the brittle truce amid sporadic fighting in eastern Ukraine.
A senior Ukrainian official told AFP that representatives of French President Francois Hollande and German Chancellor Angela Merkel are expected to visit Moscow and Kiev in the coming days to hold talks on the crisis.
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