Washington and its Arab allies opened their air assault against the extremist group last week, going after its military facilities, training camps, heavy weapons and oil installations.
The campaign expands upon the airstrikes the United States has been conducting against the militants in Iraq since early August.
The Britain-based Syrian Observatory for Human Rights said coalition forces hit Islamic State group facilities overnight in Aleppo, Raqqa, Hassakeh and Deir el-Zour provinces.
It said the gas facility itself was not damaged.
Another activist group, the Aleppo Media Center, also reported the strike on the grain silo in Manbij, northeast of Aleppo city. It said the attack ignited a fire at the facility.
There was no immediate confirmation from the US or its allies on the reported air raids.
More strikes this morning hit the town of Tel Abyad on the Syria-Turkey border, according to a resident on the Turkish side on the frontier.
Islamic State fighters cleared out of the military about three or four months ago.
