Chambers, who is also the chairman of the newly formed US-India Strategic Partnership Forum (USISPF), said the two nations can work together to create opportunities in each nation.
"We have to be careful not to misstep. You cannot go in and take a whole bunch of H1-B visas and displace 500 American workers because you can do it at lower costs. That was just a mistake. I think we have to focus on investment," Chambers told reporters here.
"Both countries can have dramatic job creation by working together and then, you have to articulate when that occurs," he said.
The US government has been critical of outsourcing firms for "unfairly" taking jobs away from US workers. In the past, it accused Infosys and its larger rival Tata Consultancy Services of "unfairly" cornering the lions share of the H-1B work visas.
Over the past few quarters, Indian IT companies have ramped up their efforts of hiring more locals in the US, which accounts for over 60 per cent of the sector's export revenues.
"We are not at all a lobbying organsition... We are a strategic organisation, a forum that is focussed on how both countries can be successful," he added.
USISPF, which includes prominent names like Indra Nooyi (Chairman and CEO, PepsiCo) and Ajay Banga (President and CEO, MasterCard), aims to promote bilateral trade.
Chambers said USISPF will work on creating meaningful opportunities that have the power to change the lives of citizens.
Chambers also lauded various steps taken by the Narendra Modi government in India like demonetisation and GST. He said these will help India in creating a "sustainable" economy.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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