The girls have also alleged that they were beaten up if tried resisting and also not provided sanitary napkins.
The Delhi Commission for Women (DCW) chief Swati Maliwal has sought an action taken report in this matter.
Police have registered a case on the basis of a complaint by the women's panel chief in which it has been alleged that this had been happening for the last two years.
They have also claimed that the conditions they lived were quite unhygienic and they were administered injections that brought about "premature growth", police said.
"We will be questioning the staff members. Medicines and injections kept at the home will be sent for forensic examination," a senior police officer said.
Currently, the statements of the girls are being recorded.
Meanwhile, Maliwal has asked for a complete list of medicines and injections which are being administered to the girls at the shelter home.
Delhi Police has registered an FIR and charged the officials running the home with criminal intimidation, causing harm by poisoning, criminal conspiracy and laws under the Juvenile Justice Care and Protection Act after the DCW reported the matter.
The Commission has also recommended immediate departmental action and transfer of seven officials of the home citing their close proximity will influence the girls who have reported brutal beatings.
Some girls have also complained in writing to the Delhi State Legal Services Authority regarding the same, the Commission mentioned in its letter.
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