With a shopping area of 72,000 square metres, the Haitang Bay duty-free shopping centre will replace an existing DFS, which is just one-seventh of the new store's size, in Sanya's downtown.
The centre has attracted nearly 300 international brands.
Several brands, including Prada, Rolex and Giorgio Armani, have appeared in a DFS on the Chinese mainland for the first time, state-run Xinhua news agency reported.
China International Travel Service Group (CITS) invested 5 billion yuan (about USD 814 million) in the centre, which is operated by China Duty Free Group.
From 2011 to 2013, Hainan saw an annual 15 per cent increase in its tourism revenue on average, with offshore duty-free sales accounting for 10 per cent of the total revenue.
Figures from the local customs show that as of mid-August, the revenue in Hainan's two DFS stores exceeded 9.2 billion yuan (about USD 1.5 billion).
