The left-hander struck seven fours and one six in his 32-ball 58 not out after Zimbabwe won the toss and elected to bat. Vusi Sibanda also made a career best 49 off 46 balls while Elton Chigumbura hit three successive sixes in his 21 off only 9 balls and Hamilton Masakadza made 39.
Shoaib Malik had the best figures of 1/23 while veterans Mohammed Shami and Shahid Afridi also got a wicket apiece.
This is the first international series in Pakistan since terrorists attacks on the Sri Lankan team bus in Lahore in 2009. Pakistan, who lead the two-match series 1-0 after winning Friday's first match by five wickets, brought in Mohammad Rizwan, Nauman Anwer and Imad Wasim as three changes.