In an update to its annual Asian Development Outlook published in April, the bank tipped regional gross domestic product to grow six percent this year, compared with its earlier forecast of 6.6 per cent. Growth in 2012 was 6.1 per cent.
It also trimmed its 2014 estimate to 6.2 per cent from the 6.7 per cent previously stated.
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On top of this are worries about the Fed's massive bond-buying programme, which saw a huge investment splurge in emerging economies when unveiled late last year but which the central bank is now considering winding down.
The ADB cut its 2013 forecasts for China to 7.6 per cent, well down from its April estimate of 8.2 per cent, blaming weaker domestic demand, a softening industrial rebound and sharp downturn in foreign trade.
"Moderating growth in the People's Republic of China is the price of structural reform as authorities engineer a medium-term transition to a more sustainable growth path than one led by exports and investment," ADB chief economist Changyong Rhee said in a statement.
"However, this growth deceleration could impact the rest of Asia... Since the PRC's economic influence has grown in the past decade," Rhee said.
India is seen growing 4.7 percent this year, compared with six percent forecast previously, with the ADB blaming a depreciation in the rupee -- it hit a record low against the dollar last month. It also cited capital outflows as foreigners repatriate their cash on expectations the Fed's stimulus will soon end.
India's economy is also hit by industry and investment bottlenecks due to poor infrastructure and delayed structural reforms, the report said.
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